The Truth About Supplements
Supplements don't replace a poor diet, but they can fill nutritional gaps and optimize performance. Most people benefit from a few foundational supplements. Everything else depends on individual needs, deficiencies, and goals.
Foundation Supplements
These supplements benefit most people due to modern diet limitations and lifestyle factors.
Vitamin D3
Strong EvidenceWhy You Need It
Most people are deficient. Critical for immune function, bone health, mood, and disease prevention. Modern indoor lifestyle limits sun exposure.
Dosing
- Maintenance: 2,000-4,000 IU daily
- Deficiency: 5,000-10,000 IU daily
- Goal: Blood level 40-60 ng/mL
- Take with: Fat for absorption
Pro Tips
- Combine with K2 (100-200 mcg) for calcium regulation
- Test blood levels 2x per year
- D3 form, not D2
- Take in morning to avoid sleep disruption
Omega-3 (EPA/DHA)
Strong EvidenceWhy You Need It
Essential fatty acids for brain function, heart health, inflammation control. Modern diet heavily skewed toward omega-6. Most don't eat enough fatty fish.
Dosing
- General health: 1-2g combined EPA/DHA daily
- Cognitive focus: Higher EPA (1-2g)
- Mood support: Higher EPA ratio
- Inflammation: 2-4g total
Pro Tips
- Choose triglyceride form over ethyl ester
- Look for IFOS or third-party testing
- Take with meals to reduce fishy burps
- Keep refrigerated
- Alternative: 2-3 servings fatty fish weekly
Magnesium
Strong EvidenceWhy You Need It
Involved in 300+ biochemical reactions. Most people deficient. Critical for sleep, muscle function, stress response, energy production, bone health.
Dosing
- Men: 400-420mg elemental magnesium
- Women: 310-320mg elemental magnesium
- Athletes: May need 500-600mg
- Timing: Evening for sleep support
Pro Tips
- Glycinate or threonate for sleep/brain
- Citrate if constipation is issue
- Oxide has poor absorption (avoid)
- Too much causes loose stools
- Can cause drowsiness
Creatine Monohydrate
Strong EvidenceWhy You Need It
One of most researched supplements. Improves strength, muscle mass, cognitive function, recovery. Safe and effective for virtually everyone.
Dosing
- Standard: 5g daily
- Loading: 20g/day for 5-7 days (optional)
- Timing: Doesn't matter, just daily
- Mix with: Water, protein shake, or food
Pro Tips
- Monohydrate is best and cheapest form
- No need for fancy variants
- May cause minor water retention (normal)
- Vegans/vegetarians benefit most
- Continue during cuts/diets
Performance & Fitness Supplements
For those training hard and looking to optimize athletic performance.
Protein Powder
Strong EvidenceWhy Use It
Convenient way to hit protein targets. Supports muscle building, recovery, and satiety. Not necessary if hitting protein through food.
Recommendations
- Target: 0.7-1g protein per lb bodyweight daily
- Whey: Fast-absorbing, post-workout
- Casein: Slow-digesting, before bed
- Plant: Pea, rice, hemp blend
Pro Tips
- Not magic—just convenient protein
- Whey isolate for lactose intolerance
- Timing matters less than total daily intake
- Look for third-party testing
Caffeine
Strong EvidenceWhy Use It
Improves focus, endurance, power output, and fat oxidation. Most studied ergogenic aid. Extremely effective pre-workout.
Dosing
- Effective dose: 3-6mg per kg bodyweight
- Typical: 200-400mg pre-workout
- Timing: 30-60 min before activity
- Daily limit: 400mg max
Pro Tips
- Coffee works as well as pills
- Tolerance develops with daily use
- Cycle off occasionally
- Cut off 8+ hours before sleep
Beta-Alanine
Moderate EvidenceWhy Use It
Buffers acid in muscles during high-intensity exercise. Delays fatigue in 60-240 second efforts. Particularly useful for CrossFit, HIIT, sports.
Dosing
- Loading: 4-6g daily for 2-4 weeks
- Maintenance: 2-3g daily
- Timing: Doesn't matter, builds up over time
- Split: 2-3 doses to reduce tingles
Pro Tips
- Harmless tingling sensation is normal
- Effects build over weeks, not immediate
- Works synergistically with creatine
- Most useful for high-intensity exercise
Sleep & Recovery Supplements
To optimize sleep quality, reduce stress, and enhance recovery.
Melatonin
Strong EvidenceWhy Use It
Regulates sleep-wake cycle. Helpful for jet lag, shift work, or difficulty falling asleep. More effective for sleep timing than sleep quality.
Dosing
- Start low: 0.3-1mg
- Standard: 1-3mg
- Maximum: 5mg (higher not better)
- Timing: 30-60 min before bed
Pro Tips
- Less is often more effective
- Use occasionally, not every night
- Best for circadian timing issues
- Can cause vivid dreams
L-Theanine
Moderate EvidenceWhy Use It
Promotes relaxation without sedation. Reduces anxiety and improves focus. Excellent paired with caffeine. Found naturally in tea.
Dosing
- Relaxation: 200-400mg
- With caffeine: 2:1 ratio (200mg theanine : 100mg caffeine)
- Sleep: 200mg before bed
- Timing: Flexible, effects within 30-60 min
Pro Tips
- Synergizes beautifully with caffeine
- Non-drowsy relaxation effect
- Safe for daily use
- 4-5 cups green tea = ~200mg
Glycine
Moderate EvidenceWhy Use It
Improves sleep quality by lowering core body temperature. Reduces time to fall asleep. Supports collagen production and gut health.
Dosing
- Sleep: 3-5g before bed
- Recovery: 10-15g daily
- Form: Pure powder (tasteless)
- Mix with: Water or herbal tea
Pro Tips
- Very safe, minimal side effects
- Can improve subjective sleep quality
- Also found in collagen and gelatin
- Sweet taste, easily mixed
Cognitive Enhancement
Supplements that support focus, memory, and brain health.
Lion's Mane Mushroom
Emerging EvidenceWhy Use It
Supports nerve growth factor (NGF) production. May improve cognitive function, memory, and neuroprotection. Popular nootropic.
Dosing
- Standard: 500-3000mg daily
- Form: Extract (30% polysaccharides)
- Timing: Morning or split doses
- Duration: 4-8 weeks for effects
Pro Tips
- Effects build over weeks
- Dual extract (water + alcohol) preferred
- Look for quality certification
- Can be added to coffee
Rhodiola Rosea
Moderate EvidenceWhy Use It
Adaptogen that reduces mental fatigue, improves stress resilience, and enhances cognitive performance during demanding tasks.
Dosing
- Standard: 200-600mg daily
- Extract: 3% rosavins, 1% salidroside
- Timing: Morning or pre-stressor
- Cycle: 4-6 weeks on, 2 weeks off
Pro Tips
- Works best during high-stress periods
- Take on empty stomach
- Can be mildly stimulating
- Quality varies significantly between brands
Supplement Selection Framework
1. Start with Foundation
Begin with Vitamin D3, Omega-3, and Magnesium. These fill the most common nutritional gaps. Test blood levels to confirm needs.
2. Add Based on Goals
Training hard? Add creatine and protein. Poor sleep? Try magnesium glycinate and glycine. Need focus? Caffeine + L-theanine.
3. Quality Over Quantity
More supplements doesn't equal better results. Choose high-quality, third-party tested products. Avoid proprietary blends.
4. Track and Adjust
Give supplements 4-8 weeks. Track how you feel. Get blood work. Drop what doesn't provide clear benefit.
5. Timing Matters
Fat-soluble vitamins with meals. Magnesium before bed. Caffeine 8+ hours before sleep. Consistency matters more than perfection.
6. Food First Always
Supplements supplement—they don't replace real food. Focus on nutrient-dense whole foods. Fill gaps with targeted supplementation.
Supplement Stack Builder
Beginner Stack (Start Here)
- Morning: Vitamin D3 (4,000 IU) + K2 (100 mcg) with breakfast
- With meals: Omega-3 (2g EPA/DHA total)
- Evening: Magnesium glycinate (400mg) 1 hour before bed
Cost: ~$30-50/month | Get blood work after 3 months
Athlete Stack
- Foundation stack (above) plus:
- Daily: Creatine (5g), anytime with water
- Pre-workout: Caffeine (200-300mg) + Beta-alanine (3g)
- As needed: Protein powder to hit daily targets
Cost: ~$60-80/month | Significant performance benefits
Sleep Optimization Stack
- Foundation stack (above) plus:
- Evening: Glycine (3-5g) before bed
- As needed: Melatonin (0.5-1mg) for circadian timing
- Afternoon: L-theanine (200mg) if anxious
Cost: ~$40-60/month | Focus on sleep hygiene first
Cognitive Performance Stack
- Foundation stack (above) plus:
- Morning: Lion's Mane (1000mg) with breakfast
- As needed: Caffeine (100mg) + L-theanine (200mg)
- Stress periods: Rhodiola (300mg) in morning
Cost: ~$50-70/month | Effects accumulate over weeks
What NOT to Waste Money On
Multivitamins
Poor absorption, low doses, unnecessary fillers. Better to target specific deficiencies with individual supplements.
Fat Burners
Mostly caffeine with unproven ingredients. Save money, drink coffee, and maintain calorie deficit.
Testosterone Boosters
Over-the-counter products don't meaningfully boost testosterone. Focus on sleep, training, and nutrition.
Detox/Cleanse Products
Your liver and kidneys detox for free. These products are expensive placebos with laxative effects.
BCAA During Meals
If eating adequate protein, BCAAs provide zero additional benefit. Complete protein is superior and cheaper.
Proprietary Blends
Hide ingredient amounts. Impossible to verify dosing. Choose transparent labels with specific amounts listed.